PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis
Status:
Completed
Trial end date:
2020-10-28
Target enrollment:
Participant gender:
Summary
The proposed project will be the first to assess pain- and function-dependent, elbow-specific
quality of life and in-vivo mechanical properties of common extensor tendons post-treatment
with PRP in a Level 1, RCT with subject and assessor blinding. The valuable data gained will
significantly add to the knowledge base of treatment effects of PRP for a chronic
tendinopathy. Positive findings of PRP compared to control (corticosteroid injection) would
suggest future larger scale studies to help establish an optimal protocol for the nonsurgical
management of CLE. Correlating US and shear wave acoustoelastography imaging assessments with
validated clinical outcomes will provide a powerful tool for future outcomes analyses using a
non-invasive imaging modality to monitor tissue healing both morphologically as well as
biomechanically, and may even be used to evaluate injury risk.