Overview

PDE4 Inhibition in Seborrheic Dermatitis and Papulopustular Rosacea

Status:
TERMINATED
Trial end date:
2025-02-18
Target enrollment:
Participant gender:
Summary
This study is a double-blind, vehicle-controlled clinical trial. The study will take place at Icahn School of Medicine at Mount Sinai. The study will include 33-39 adult subjects with moderate-to-severe-Seborrheic dermatitis (SD) as well as 33-39 adult subjects with moderate-to-severe papulopustular rosacea (PPR). Subjects will be randomized 2:1 to receive study drug or placebo. Enrolled subjects will apply topical PF-07038124 0.02% ointment once daily for 8 weeks. They will return for visits at weeks 4, 8, and 12 following study treatment initiation for repeat clinical assessments, medication reviews, tape-strip, blood and urine sample collections, and monitoring for adverse events.
Phase:
PHASE2
Details
Lead Sponsor:
Icahn School of Medicine at Mount Sinai
Collaborator:
Pfizer