Overview

PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations

Status:
Completed
Trial end date:
2018-12-15
Target enrollment:
Participant gender:
Summary
The purpose of this trial is to evaluate 2-year disease-free survival in this patient population treated with single agent cisplatin and patients treated with cisplatin in combination with Rucaparib following preoperative chemotherapy. Side effects and tolerability of this treatment in patients with residual disease following preoperative chemotherapy will also be observed and characterized.
Phase:
Phase 2
Details
Lead Sponsor:
Hoosier Cancer Research Network
Collaborator:
Clovis Oncology, Inc.
Treatments:
Cisplatin
Rucaparib