PAIN - Postoperative Analgesia INvestigation

• Status: Completed
• Trial end date: 2017-06-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the efficacy of the intraoperative injection of prolonged acting (liposomal) bupivacaine in postoperative pain control after truncal surgical incisions.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Texas Health Science Center, Houston
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• 18 years-old or older, and

• Sternotomy, thoracotomy, laparotomy or mini-thoracotomy incision is planned

• There is reasonable expectation that the patient will be extubated within 24 hours after surgery

Exclusion Criteria:

• The patient has a known allergy to morphine or any opioid

• The patient has a known chronic pain disorder or takes daily opioid medication > 1 month prior to surgery

• There is anticipated difficulty communicating pain status due to language or other barriers at the investigator discretion

• High postoperative morbidity index based on preoperative assessment, such as, low likelihood of extubation within 24 hours, extensive thoracoabdominal aortic aneurysm (Extent 2 TAAA), preoperative renal insufficiency/failure, etc.