This will be a laboratory-based investigation of the behavioral and neural effects of
intranasal oxytocin on craving for alcohol and approach bias in moderate to heavy alcohol
using subjects. This study uses a within-subject, randomized, placebo-controlled,
counterbalanced, crossover design to compare the effects oxytocin and placebo. In this way,
all subjects will be scanned twice; once following oxytocin administration and once following
placebo administration, and will complete a series of behavioral tasks (both in and out of
the scanner) at both visits.
Phase:
Phase 2
Details
Lead Sponsor:
Jennifer Mitchell University of California, San Francisco