Individuals with Prader-Willi syndrome (PWS) have been found to have a deficit of
oxytocin-producing neurons and decreased oxytocin receptor gene function, so the purpose of
this study is to determine if oxytocin (OT) administration will improve some of the aspects
of Prader-Willi syndrome that are particularly troublesome for children and their families
(the insatiable appetite and social behaviors).
The research questions are:
1. Does intranasal oxytocin cause any side effects in children with PWS?
2. Does intranasal oxytocin administration alter appetite or behaviors in PWS?