Purpose: The purpose of this research study is to learn whether oxytocin treatment decreases
use of and cravings for opioids (narcotics) in people who have been using opioids heavily for
long periods of time and are unable to stop on their own.
Participants: Patients meeting DSM-IV-TR criteria for opioid dependence.
Procedures (methods): Subjects will have standard medications available for withdrawal
symptoms from opioids and standard psychosocial interventions available in the inpatient
setting. In addition, subjects will self-administer intranasal test treatments 3 times daily.