Oxidized Omega-3 Supplements With Different Oxidation
Status:
Completed
Trial end date:
2011-04-01
Target enrollment:
Participant gender:
Summary
The oxidation level of unsaturated fatty acid supplements commercialized in capsules could be
a serious problem for manufacturers and a risk to consumers; health by ingesting substances
whose effects are not desired. Therefore, the main objective of this paper is to analyze the
effect of dietary supplements Omega-3 with different levels of oxidation in the lipid profile
of women who consume these supplements. For this purpose the investigators have designed a
single-blind, parallel-groups, randomized controlled trial. Finally, 52 women between 25 and
75 years old were randomly distributed into three groups: (1) took 2 capsules/day of one of
the less oxidized oil (containing 300 mg EPA + DHA) and diet, (2) took 2 capsules/day of one
of the most oxidized oil (containing 300 mg EPA + DHA) and diet and (3) no capsules, only
received the diet. There was a 30 days follow-up . All groups followed a low cholesterol
diet. Circulating glucose, total cholesterol, triglycerides and glutamic pyruvic transaminase
were determined at the beginning and end of a 30 day period.
Phase:
N/A
Details
Lead Sponsor:
Universidad Miguel Hernandez de Elche
Collaborators:
Instituto de Salud Carlos III University of Alicante