Ovulation and Follicular Development Associated With Mid Follicular Phase Initiation of Combined Hormonal Contraception

• Status: Completed
• Trial end date: 2018-02-28
• Target enrollment: 0
• Participant gender: Female

Summary

Quick starting combined oral contraception containing estradiol hemihydrate/nomegestrol acetate is effective to inhibit ovulation in healthy reproductive age women and non-inferiority to combined oral contraception containing ethinyl estradiol/gestodene.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mahidol University
• Treatments: Estradiol; Estradiol 17 beta-cypionate; Estradiol 3-benzoate; Estradiol valerate; Ethinyl Estradiol; Polyestradiol phosphate

Criteria

Inclusion Criteria:

• healthy women, age 18 - 40 years

• prior normal and regular interval of menstruation

Exclusion Criteria:

• current breast feeding women

• within 1 month period of child-delivery or miscarriage

• body mass index 30 kg/m2 or more

• contraindicated to use combined hormonal contraception

• current using other hormonal drugs that affect ovulation function