Overcoming Psychomotor Slowing in Psychosis (OCoPS-P)
Status:
Recruiting
Trial end date:
2024-01-01
Target enrollment:
Participant gender:
Summary
Psychomotor slowing is a major problem in psychosis. Aberrant function of the cerebral motor
system is linked to psychomotor slowing in patients, particularly resting state hyperactivity
in premotor cortices. A previous clinical trial indicated that inhibitory stimulation of the
premotor cortex would reduce psychomotor slowing. The current study is further exploring this
effect in a randomized, placebo-controlled, double-blind design with three arms of
transcranial magnetic stimulation and measures of brain imaging and physiology prior to and
after the intervention.