Overview

Ovarian Contribution to Androgen Production in Adolescent Girls

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Women with polycystic ovary syndrome (PCOS) can have unwanted facial or male-patterned body hair, irregular menstrual periods, or no menstrual periods excess body weight, and infertility. It also results in elevated androgen levels such as testosterone. In women with PCOS, the majority of excess androgens are produced by the ovaries. However, it is unknown whether the ovaries are fully active during early puberty. The purpose of this study is to determine how the ovaries contribute to the production of male hormones in the body during different stages of puberty, so that it can be better understood why some females have excess androgens.
Phase:
N/A
Details
Lead Sponsor:
University of Virginia
Collaborator:
University of California, San Diego
Treatments:
Androgens
BB 1101
Chorionic Gonadotropin
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate