Within the epidemic context of phase 3 in Mexico, the implementation of new treatments that
have been shown to be beneficial for patients in other countries is an urgent need. Methylene
blue (MB, the oxidized form, blue color) has been used in many different clinical medicine
areas, ranging from malaria to orthopedics. Methylene blue absorbs energy directly from a
light source and then transfers this energy to molecules of oxygen creating singlet oxygen
(O2), which is the first electronic excited state of molecular oxygen (O2). Singlet oxygen is
extremely electrophilic; thus, it can directly oxidize electron-rich double bonds in
biological molecules and macromolecules. For this reason, methylene blue has been used as a
photosensitizer in the treatment of cancer and the protection of serum from viral agents.
Methylene blue can be reactivated using energy from a light source in the body until
processed out through the kidneys.