Overview Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma Status: Completed Trial end date: 2012-10-01 Target enrollment: Participant gender: Summary The primary purpose of this study is to determine the safety and feasibility of delivering HDMTX in an outpatient setting. Phase: Phase 3 Details Lead Sponsor: The Hospital for Sick ChildrenTreatments: Methotrexate