Outcomes of Non-infected Diabetic Foot Ulcers With/Without Antibiotics
Status:
Unknown status
Trial end date:
2012-02-01
Target enrollment:
Participant gender:
Summary
The overall objective is to investigate whether antibiotics in the treatment of clinically
clean neuropathic and ischaemic ulcers in diabetic foot patients could reduce the incidence
of infection and therefore lead to improved outcomes This is a single centre study in which
patients with either type 1 or 2 diabetes mellitus, who consecutively present to the Diabetic
Foot Clinic [DFC] with clean neuropathic (NU) or ischaemic (IU) diabetic foot ulcer without
clinical signs of infection will be invited to take part and will express their willingness
to take part in the study by signing a consent form.
- All patients will be treated and followed up in the DFC at King's College Hospital.
Patients will be randomised into two groups: an antibiotic group and a control group.
- The antibiotic group will receive standard treatment along with antibiotics.
- The control group will have standard treatment alone.
- Patients from both groups will be reviewed at weekly intervals for a period of 20 weeks.
- Patients will be removed from the study if they develop clinical signs of infection or
if their ulcer heals prior to 20 weeks but will be followed up via routine practice for
eventual outcomes