Outcomes With Tight Control of Hyperglycemia in Cardiac Surgery Patients

• Status: Completed
• Trial end date: 2005-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients with or without diabetes may have high blood sugar levels due to stress response of the body during heart surgery. This study is being done to determine if maintaining normal blood sugar levels during open-heart surgery by using intravenous insulin results in a lesser incidence of death, wound infections in the chest, disturbances of heart rhythm, kidney failure, stroke and prolonged time on the breathing machine (artificial ventilation) within 30 days after surgery.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mayo Clinic
• Collaborator: Novo Nordisk A/S
• Treatments: Insulin

Criteria

Inclusion Criteria

All subjects accepted for this study must be:

1. >=18 years of age

2. Undergoing an elective cardiac surgical procedure

Exclusion Criteria

Subjects who have one or more of the following will be excluded from the study:

1. Undergoing surgery not utilizing cardiopulmonary bypass

2. Unable to grant informed consent or comply with study procedure

3. Undergoing emergency open heart-surgery

3. Are allergic to any of the excipients in insulin