Overview

Oral vs Intravenous Acetominophen for Postoperative Pain in Minimally Invasive Gynecologic Surgery

Status:
Unknown status
Trial end date:
2018-02-01
Target enrollment:
0
Participant gender:
Female
Summary
Hypothesis: Postoperative pain will be equivalent in patients receiving preemptive oral acetaminophen as compared to patients receiving preemptive intravenous acetaminophen following minimally invasive benign gynecologic surgery. Primary outcome: • Difference in postoperative pain comparing preemptive use of PO versus IV acetaminophen o Mean Visual analog Scale (VAS) scores will be compared between the intervention group (PO acetaminophen) and the control group (IV acetaminophen). Secondary outcomes: - Difference in postoperative analgesic use between groups o Narcotics, NSAIDs - Difference in postoperative N/V between groups o Patient rated measure - none, mild, moderate, severe - Cost comparison between drugs
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Scripps Health
Treatments:
Acetaminophen
Criteria
Inclusion Criteria:

- Patients 18 years of age or older scheduled to undergo robotic-assisted laparoscopic
hysterectomy for benign conditions.

Exclusion Criteria:

- Known or suspected malignancy,

- Active liver/renal disease,

- Chronic alcohol use/alcoholism,

- Allergy to acetaminophen,

- Conversion to laparotomy,

- hx gastroparesis,

- Poorly controlled insulin dependent diabetes or gastric bypass surgery,

- Regular/recent (past 6 months) narcotic use,

- Inability to swallow pills.