Oral Versus Intravenous Hydration to Prevent Contrast Induced Nephropathy

• Status: Terminated
• Trial end date: 2014-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate if home-hydration is a non inferior alternative for in-hospital hydration in the prevention of Contrast Induced Nephropathy in high risk patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Prof. Dr. J. Wetzels

Criteria

Inclusion Criteria:

• Adult patients > 18 years undergoing an elective procedure involving intravascular administration of iodinated contrast media

• high risk for the development of Contrast Induced Nephropathy (as defined by guideline criteria

Exclusion Criteria:

• Age < 18.

• Low risk for the development of CIN, therefore no need for hydration

• Emergency contrast procedure.

• Overt signs of overhydration; orthopnea or pulmonal rales at the time of the first consult.

Double or triple diuretic use for pre-existing heart failure. Severe heart failure, in which case salt load is not safe (physician decision) Severe renal failure (CKD stage V eGFR < 15ml/min/1.73m2) Multiple Myeloma. Repeated contrast exposure < 2 weeks Unstable serum creatinine > 25% change < 6 weeks The inability to provide written informed consent. Participation in another intervention study