Overview

Oral Vancomycin Versus Probiotics Versus Placebo for Prevention of Clostridium Difficile Infection in Colonized Patients

Status:
Not yet recruiting

Trial end date:
2021-03-01

Target enrollment:

Participant gender:

Summary

The goal of this pilot study is to assess the feasibility of randomizing hospitalized patients that are colonized with C. difficile and started on systemic antibiotics to either a probiotic, oral vancomycin, or placebo in a parallel-group 1:1:1 design. The ultimate goal is to conduct an appropriately-powered RCT to determine the optimal method for reducing C difficile infection in colonized patients.

Phase:

Early Phase 1

Details

Lead Sponsor:

Hamilton Health Sciences Corporation

Treatments:

Vancomycin