Oral Steroids in Chronic Rhinosinusitis Without Nasal Polyps
Status:
Completed
Trial end date:
2019-01-01
Target enrollment:
Participant gender:
Summary
Chronic rhinosinusitis is a common disease that effects millions of people world wide.
Despite its frequency it is unclear what treatment options are the best for these patients.
Typically patients with chronic rhinosinusitis without nasal polyps (CRSsNP) are given a long
term antibiotic (3 weeks), nasal steroid sprays, saline nasal irrigation and occasionally
oral steroids. Oral steroids benefit patients with chronic rhinosinusitis with nasal polyps
(CRSwNP) however their role in non polyp patients is less clear. It is the goal of this study
to see if oral steroids benefit the treatment outcomes in those patients with chronic
rhinosinusitis without nasal polyps. In addition this study will look to see if a short
course (5 day burst) versus a longer course (21 day taper) of oral steroids make a difference
in outcomes.