Oral Sedation During Cervical Dilator Placement

• Status: Completed
• Trial end date: 2019-05-28
• Target enrollment: 0
• Participant gender: Female

Summary

This will be a randomized, double-blind, placebo-controlled trial involving 2 arms. It will be comparing the effects of placebo compared to 1 mg oral lorazepam/5 mg oral oxycodone on pain scores during cervical dilator placement prior to dilation and evacuation (D&E).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johns Hopkins University
• Collaborator: Society of Family Planning
• Treatments: Lorazepam; Oxycodone

Criteria

Inclusion Criteria:

• Women aged 18-50 years

• English speaking

• With an intrauterine pregnancy (either viable or non-viable) between the gestational ages of 17w0d and 23w6d

• Have a support person present with participant

• Have a cell phone capable of text messaging (optional)

Exclusion Criteria:

• Non-English-speaking

• Taking a daily benzodiazepine or opiate

• Have a known allergy or contraindication to NSAIDs, opiates, or benzodiazepines