Oral Navelbine and Cisplatin Followed by Metronomic Oral Navelbine in Non-Small Cell Lung Cancer
Status:
Terminated
Trial end date:
2018-04-01
Target enrollment:
Participant gender:
Summary
This is an open-label, multi-center clinical trial, aims to evaluate the efficacy and safety
of combination of oral Navelbine and Cisplatin followed by metronomic oral Navelbine in
Patients with advanced Non-Small Cell Lung Cancer.
The study comprises two stages. In the 1st stage (Week 1-12), all patients will receive
combination chemotherapy. In the 2nd stage (Week 13-25), patients who complete the
combination chemotherapy with acceptable tolerance and have no progressive disease (PD) will
be allocated into 2 arms, to evaluate the efficacy and safety of maintenance chemotherapy
with metronomic oral Navelbine (Arm A) or other regimen (Arm B).