Oral Medications for the Management of Acute Migraine Headache in the Emergency Department
Status:
Not yet recruiting
Trial end date:
2024-06-30
Target enrollment:
Participant gender:
Summary
The goal of this pilot randomized control trial is to assess the feasibility of our patient
recruitment and data collection strategy ahead of a full scale RCT investigating the efficacy
of oral v. parenteral medications in the management of acute migraine headaches in the
emergency department. Patients will be randomly assigned to receive either (A) standard
medical therapy for the treatment of acute migraine headache (metoclopramide and ketorolac
IV) and oral placebo or (B) oral metoclopramide and ibuprofen with normal saline IV. Primary
outcome measures are recruitment rate and improvement in pain score at 60 minutes from
medication administration.