Oral Isotretinoin for Photoaging: Results of a Randomized Controlled Phase II Trial
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
A clinical and histological randomized controlled phase II trial to evaluate the efficacy and
safety of oral isotretinoin for treating photoaging was performed with 32 menopausal or
sterilized women aged 40-55y. The subjects were included in two randomly selected groups: A-
21 women received 20mg oral isotretinoin 3x week, moisturizer, sunscreen SPF 60 during three
months; B- 11 women received only same moisturizer/sunscreen.