Oral Flurbiprofen Spray for Mucosal Graft Harvesting at the Palatal Area
Status:
Completed
Trial end date:
2017-03-01
Target enrollment:
Participant gender:
Summary
Connective tissue graft (CTG) and free gingival graft (FGG) harvesting from the palatal area
has been used frequently in the periodontal mucogingival surgery and reported to provide
higher predictability and success regarding esthetic outcomes. The aim of the study was to
evaluate the effects of oral flurbiprofen spray on wound healing, postoperative patient
morbidity and discomfort after palatal graft harvesting.
Forty eight patients scheduled for CTG and FGG requiring periodontal plastic surgeries were
selected. The patients were randomly assigned to each group, and used oral spray of
flurbiprofen or placebo 3 times a day for a week. The palatal donor area was evaluated at 1
and 3 days and 1, 2, 3, 4, 6 and 8 weeks postsurgery for postoperative pain, complete
epithelization, feeding habits, color match, and total number of analgesic pills taken. The
Wound-Healing Index (WHI) was recorded at 2-week follow up.