Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR)

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Male

Summary

To evaluate the efficacy of oral colchicine combined with intraoperative infusion of dexamethasone, low molecular weight heparin and 5-FU during vitrectomy for management of established proliferative vitreoretinopathy (PVR)

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shahid Beheshti University of Medical Sciences
• Treatments: BB 1101; Calcium heparin; Colchicine; Dalteparin; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Heparin; Heparin, Low-Molecular-Weight; Tinzaparin

Criteria

Inclusion Criteria:

• Cases with rhegmatogenous retinal detachment complicated by PVR grade C

Exclusion Criteria:

• History of pars plana vitrectomy for PVR grade C

• History of silicone oil injection

• History of ocular trauma

• Diabetic retinopathy

• Glaucoma

• Giant retinal tear