Oral Changes With Caloric and no Caloric Sweeteners

• Status: Not yet recruiting
• Trial end date: 2024-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this clinical trial is to compare the effect that the intake of beverages added with non-caloric sweeteners (stevioside) and caloric sweeteners (sucrose) on oral pH and dental biofilm microbiome in Mexican adolescents.

Participants will drink on different occasions a beverage without sweetener, a beverage added with stevioside or a beverage added with sucrose. The researchers will compare the changes that each one causes in salivary pH, dental biofilm pH, dental biofilm bacterial proliferation and dental biofilm microbiome.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hospital Infantil de Mexico Federico Gomez

Criteria

Inclusion Criteria:

• Habitual consumption of soft drinks

• Decayed, Missing, and Filled Teeth (DMF) index of at least 3

• Agree to participate in the study and sign informed consent

• Parents sign informed consent

• Any nutritional condition

Exclusion Criteria:

• Orthodontic treatment

• Topical application of fluoride during the last 3 months

• Having a motor disability that interfered with tooth brushing

• Xerostomia

• Antibiotic therapy during the study period

• Periodontal infections