Cannabidiol is a compound found in cannabis plants that is well tolerated, has low abuse
liability, and might be an effective medication to promote tobacco cessation. This clinical
study will use a validated approach for screening tobacco cessation medications to determine
if oral cannabidiol increases short-term tobacco abstinence, and evaluate mechanisms that
might explain how cannabidiol alters smoking behavior. Results from this study will provide
data on the therapeutic potential of cannabidiol for tobacco cessation.