Oral Baclofen Pharmacokinetics and Pharmacodynamics in Children With Spasticity
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
Oral baclofen is used commonly to treat spasticity in children with cerebral palsy. Although
for adults there is dosing,safety and efficacy information in the package insert, this is not
the case for children. The purpose of this study is to determine how fast the drug is cleared
from the body, the correct dose, and long-term safety and efficacy for children with
spasticity.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)