Optimum Dose of Remifentanil for Intubation in Small Children
Status:
Completed
Trial end date:
2008-04-01
Target enrollment:
Participant gender:
Summary
The routine medications to relax the muscles of the throat are an anesthetic drug, propofol,
in combination with an ultra short acting pain medicine, remifentanil. Remifentanil is used
to reduce the amount of propofol required but also to decrease the natural cough reflex to
the breathing tube being inserted.The purpose of this study is to find the dose of
remifentanil when combined with propofol which provides the best conditions for intubation
without cough in infants and small children.Younger children may need higher doses of
Remifentanil to facilitate intubation as they are more tolerant to the respiratory depressant
effect of Remifentanil.