Optimizing Pain Control in Transurethral Resection of the Prostate

• Status: Unknown status
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to develop a multi-modal protocol for pain management after TURP that minimizes opioid use. The investigators hypothesize this approach will provide non-inferior pain control to the current standard of care which includes opioids as the primary agent. The investigators believe this is an important step in reducing the opioid epidemic in surgical patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Benaroya Research Institute
• Collaborator: Virginia Mason Hospital/Medical Center
• Treatments: Ibuprofen; Oxycodone

Criteria

Inclusion Criteria:

• Are identified as candidates for TURP

• Are 18 years of age or greater

• Are proficient in English

Exclusion Criteria:

• Have filled an opioid prescription in the last 2 months

• Have an allergy to a medication included in the protocol

• Have a history of pelvic radiation

• Have renal failure (Serum Cr > 2.0 mg/dl), peptic ulcer disease, history of gastric bypass, cirrhosis, or other contraindication precluding use of NSAID's

• Have liver failure, hepatitis, or alcohol abuse which precludes use of acetaminophen