Optimizing Ovulation Induction in the Poor Responder
Status:
Withdrawn
Trial end date:
2012-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this randomized controlled trial is to compare the efficacy and effect of
luteal estradiol and combined oral contraceptive pills (COPC) on follicle recruitment and
synchrony in a poor responder population. The randomized groups consist of: 1. patients
receiving luteal estradiol prior to ovulation induction; and 2. patients receiving COCPs for
1 month prior to ovulation induction. Follicle characteristics and serum biomarkers will be
followed and compared in each group. Coefficient of variation will be used to evaluate
follicle size discrepancy. Chi square analysis will be used to compare categorical variables
between treatment groups. Both estradiol and COPCs are used clinically in assisted
reproduction, so this study affords no additional risks to the participants.