Optimizing Metformin Use in Polycystic Ovary Syndrome
Status:
NOT_YET_RECRUITING
Trial end date:
2028-12-31
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to learn if a metformin dose of 1500 mg or 2250 mg per day is better to treat polycystic ovary syndrome (PCOS) in adults. It will also learn about the adverse effects of metformin. The trial aims to evaluate which metformin dose is better for:
1. improving biochemical and clinical outcomes
2. gastrointestinal side-effects
3. mental health and quality of life
Participants will:
* Be randomized to take metformin at a dose of either 1500mg or 2250mg every day for 6 months
* Visit the clinic three times during the trial for checkups and tests
* Answer questionnaires on menstrual cyclicity, mental health, quality of life and side-effects
Phase:
PHASE3
Details
Lead Sponsor:
Helsinki University Central Hospital
Collaborators:
Sakari Alhopuro foundation (funding) The Medical Society of Finland (funding) Valtion tutkimusraha (funding)