Optimizing Body Composition for Function in Older Adults
Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this pilot study is to compare two strategies intended to improve the health
of overweight older adults by improving body composition. One strategy, resistance training,
is designed to preserve skeletal muscle mass. The other strategy, the use of a PPAR-γ
agonist, is designed to enhance the loss of fat from visceral and skeletal depots. These
strategies will be used in conjunction with a hypocaloric diet and will be compared to a
hypocaloric diet alone to determine if either of these strategies are superior in reducing
visceral fat and preserving muscle mass.
Phase:
Phase 4
Details
Lead Sponsor:
Wake Forest Baptist Health Wake Forest University Health Sciences
Collaborators:
National Institute on Aging (NIA) Takeda Pharmaceuticals North America, Inc.