Optimised Fluoride Prevention by Double Rinse With Fluoride and Calcium
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
Aim: to determine the optimal Ca2+ concentration with 905 ppm F as NaF. Study design:
Experimental study in 10 volunteers. Single blind mouth rinse with calcium lactate solution
(150; 75; 0 mM Ca-lactate) is immediately followed by a standard fluoride rinse.
Procedure: Rinses are performed in the evening. The rinse combinations are given in a random
order, and the subjects are unaware of the sequence. At least 3 days separates the use of
each rinse. Dosage: 20 mL and 1 minute rinse with each solution.
Saliva samples: Twelve hours after rinsing, unstimulated saliva samples are collected by
expectoration.
Analysis: The fluoride concentration in saliva samples are analysed Statistics and data
handling: Fluoride in saliva 12 hours after rinsing are examined by one-way ANOVA, repeated
measures design.