Optimal Timing of Dronedarone Initiation After Conversion in Patients With Persistent Atrial Fibrillation
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
Primary Objective:
- Evaluate the rate of Atrial Fibrillation (AF) recurrences one month after randomization
according to different timings of initiation of dronedarone.
Secondary Objective:
- Evaluate the rate of AF recurrences two months after randomization.
- Assess the safety of the change from amiodarone to dronedarone
- Assess dronedarone safety
- Explore dronedarone and its active metabolite plasma level (in a subset of countries)
- Explore potential Pharmacokinetic (PK) interaction between dronedarone and amiodarone
(in a subset of countries)