Optimal Sevoflurane Concentration for Intubation in Combination of Clincal Remifentanil Doses
Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
Intubation is a procedure that requires well relaxed muscles while general anesthesia is
performed. In order to get adequate muscle relaxation, remifentanil, sevoflurane or both
agents in combination have been reported as they can provide adequate conditions for
laryngoscopy and tracheal intubation without using muscle relaxants.
However, there were no previous studies to find the effective dose of sevoflurane in
combination with different bolus doses of remifentanil to obtain adequate endotracheal
intubation conditions without using muscle relaxants. The aim of this study is to investigate
the change in the minimum sevoflurane alveolar concentration which produces an adequate
endotracheal intubation condition when sevoflurane is combined with different bolus doses of
remifentanil used in clinical practice.