Optimal Multimodal Analgesia in Abdominal Hysterectomy

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to test the current standard of care (SOC) treatment for abdominal hysterectomy with a group receiving SOC minus epidural analgesia plus additional perioperative analgesics in terms of postoperative abilities, postoperative nausea and vomiting (PONV), pain and discharge time from the PACU (post-anaesthesia care unit).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hvidovre University Hospital
• Treatments: Esketamine; Gabapentin; Ketamine; Lidocaine

Criteria

Inclusion Criteria:

• Planned abdominal hysterectomy with or without BSO

• Age above 18 years

• Written informed consent

• American Society of Anesthesiologists (ASA) class I-III

Exclusion Criteria:

• Planned vaginal or laparoscopic hysterectomy

• Hysterectomy as part of other surgery

• Allergy to part of the treatment regimen

• Previous reactions to opioids (nausea, cognition)

• Previous inability to place correct epidural catheter

• Severe state anxiety according to the OCAP or STAI

• ASA class IV

• Dependency on alcohol, opioids or central stimulants

• Chronic pain condition

• Hemorrhagic diathesis

• Participation in another study