Overview

Optimal Dose of i.v Oxycodone for Postoperative Pain

Status:
Completed
Trial end date:
2018-07-01
Target enrollment:
0
Participant gender:
All
Summary
Postoperative pain control is required after major abdominal surgery, including laparoscopic colorectal surgery. Intravenous oxycodone is widely used for postoperative acute pain control mainly in Europe. The aim of this study is to evaluate the optimal dose of intravenous oxycodone for pain control after laparoscopic colorectal surgery in Korean.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Seoul National University Hospital
Treatments:
Oxycodone
Criteria
Inclusion Criteria:

- American Society of Anesthesiologists class 1, 2

- Expected surgical time between 2~ 6hours

- Scheduled for laparoscopic colorectal surgery

Exclusion Criteria:

- Severe dysfunction of liver, heart, kidney, or lung

- Cannot understand numeric rating scale of pain

- Known or suspected allergy to oxycodone

- Previous history of postoperative nausea or vomiting

- Medication of antidepressants

- Postoperative longterm

- ICU care or prolonged mechanical ventilatory support

- Chronic pain

- Drug abuser

- Hypersensitivity reaction to aspirin or NSAIDs

- Refuse to enroll