Optimal Dose of i.v Oxycodone for Postoperative Pain After Laparoscopic Colorectal Surgery

• Status: Withdrawn
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Postoperative pain control is required after major abdominal surgery, including laparoscopic colorectal surgery. Intravenous oxycodone is widely used for postoperative acute pain control mainly in Europe. The aim of this study is to evaluate the optimal dose of intravenous oxycodone for pain control after laparoscopic colorectal surgery in Korean.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Oxycodone

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists class 1,2

• Expected surgical time between 2 - 6 hours

• Scheduled for laparoscopic colorectal surgery

Exclusion Criteria:

• Severe dysfunction of liver, heart, kidney, or lung

• Cannot understand numeric rating scale of pain

• Known or suspected allergy to oxycodone

• Previous history of postoperative nausea or vomiting

• Medication of antidepressants

• Postoperative long-term ICU care or prolonged mechanical ventilatory support

• Chronic pain

• Drug abuser

• Hypersensitivity reaction to aspirin or NSAIDs

• Refuse to enroll