Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea. The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oregon Health and Science University
• Collaborator: National Eye Institute (NEI)

Criteria

Inclusion Criteria:

• Patients with vision primarily limited by superficial opacities and irregularities that could be removed by PTK while leaving at least 250 µm.

Exclusion Criteria:

• Inability to give informed consent

• Inability to maintain stable fixation for OCT imaging

• Inability to commit to required visits to complete the study

• Deep corneal opacities and irregularities

• Cataracts, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery