Opioid-free Anesthesia in Thyroidectomies

• Status: Not yet recruiting
• Trial end date: 2024-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective thyroidectomies. Recovery parameters and nociception levels throughout the operation will be evaluated

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Aretaieion University Hospital
• Treatments: Dexmedetomidine; Ketamine; Lidocaine; Remifentanil

Criteria

Inclusion Criteria:

• adult patients

• American Society of Anesthesiologists (ASA) classification I-II

• elective thyroidectomy

Exclusion Criteria:

• body mass index (BMI) >35 kg/m2

• contraindications to local anesthetic administration

• systematic use of analgesic agents preoperatively

• chronic pain syndromes preoperatively

• neurological or psychiatric disease on treatment

• pregnancy

• severe hepatic or renal disease

• history of cardiovascular diseases/ arrhythmias/ conduction abnormalities

• bradycardia(<55 beats/minute)

• drug or alcohol abuse

• language or communication barriers lack of informed consent