Opioid Sparing Anaesthesia for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
Status:
Completed
Trial end date:
2021-05-26
Target enrollment:
Participant gender:
Summary
In spite of multimodal analgesic strategies, which consist of opioids, dexamethasone,
non-steroidal anti-inflammatory drugs, and local anesthetics applied into the surgical wound,
postoperative pain and postoperative nausea and vomiting (PONV) are still common complaints
reported after laparoscopic gynecological surgery.
So, it is hypothesized that the infusion consisting of lidocaine, dexmedetomidine and
ketamine, as an opioid substitute was a feasible technique for laparoscopic gynecological
surgery and would be associated with less incidence of PONV and lower opioid requirements in
the early postoperative period.
The aim of this study was to evaluate the effect of opioid sparing technique via infusion of
Dexmedetomidine, Ketamine and Lidocaine on post-operative nausea and vomiting in laparoscopic
gynecological surgery.