Opioid Rotation Versus Combination for Chronic Uncontrolled Cancer Pain
Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
Participant gender:
Summary
For cancer patients with inadequate pain relief, a switch to an alternative opioid is the
preferred option for symptomatic improvement. However, multiple opioids are often
simultaneously administered for anecdotal reasons.
The present study isdesigned to assess the analgesic profiles of two different strategies in
chronic cancer pain: the opioid rotation from oxycodone to transdermal fentanyl and the
combination of oral oxycodone and transdermal fentanyl.