Opioid Induced Bowel Dysfunction in Patients Undergoing Cesarean Section

• Status: Unknown status
• Trial end date: 2017-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Constipation is common in pregnant women. Surgery, anaesthesia and opioid analgesics may further impair bowel function. The aim of the present study was to evaluate if oxycodone-naloxone combination compared to oxycodone reduced bowel dysfunction in patients undergoing caesarean section.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kuopio University Hospital
• Collaborator: Admescope Ltd
• Treatments: Naloxone; Oxycodone

Criteria

Inclusion Criteria:

• • elective caesarean section in spinal anaesthesia

• normal full term single pregnancy

• age 18 years or more

• BMI 20 - 35 kg/m2

• written informed consent obtained

Exclusion Criteria:

• • not normal or full term pregnancy

• age less than 18 years

• allergy to study drugs

• substance misuse other contraindication to used study drugs no informed consent