Opioid Free Anesthesia and Major Spine Surgery

• Status: Recruiting
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study compares the intraoperative opioid free anesthesia approach in multilevel spine posterior instrumentation surgery to a conventional opioid-based anesthesia. Half of participants will receive opioid free anesthesia with dexmedetomidine, lidocaine and ketamine while the other half will receive opioid based anesthesia with fentanyl, remi-fentanyl and ketamine

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lebanese American University
• Treatments: Analgesics, Opioid; Anesthetics; Dexmedetomidine; Lidocaine

Criteria

Inclusion Criteria:

• Age group: 18-80 years old

• American Society of Anesthesiologists (ASA )class I, II and III

• Elective spine posterior instrumentation surgery of at least two levels.

Exclusion Criteria:

• Renal, hepatic or cardiac insufficiency.

• Alcohol or drug abuse.

• Psychiatric disease.

• Allergy or contraindication to any of the study drugs.

• Inability to comprehend pain assessment or inability to use a Patient Controlled Analgesia (PCA) device.