Opioid Effects on Swallowing and Esophageal Sphincter Pressure
Status:
Completed
Trial end date:
2010-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether a dopamine receptor antagonist
metoclopramide can counteract opioid induced effects on esophageal motility and lower
esophageal sphincter. The aim of this study is also to evaluate if the opioid antagonist
naloxone reduces the opioid induced pharyngeal and esophageal dysfunction.