Opioid Based Anaesthesia vs Opioid Free Anesthesia in Cleft Lip, Palate ,Alveolus Surgery.
Status:
Unknown status
Trial end date:
2020-10-04
Target enrollment:
Participant gender:
Summary
Peri-operative opioid administration has long been one of the three pillars of 'balanced
anaesthesia',over the span of just a few years,opioids were widely used in perioperative
analgesia because of pain as the fifth vital sign.However, opioid administration is not
without concern and is associated with many side-effects such as constipation, urinary
retention, respiratory depression and postoperative nausea and vomiting .Cleft
lip,palate,alveolus are common craniofacial abnormalities and usually require surgical
repair.These patients have risks for various perioperative complications due to their young
age and craniofacial abnormalities.
This study was designed to compare the effects of opioid based anesthesia（OBA） and opioid
free anesthesia(OFA )on perioperative complications in patients with in cleft
lip,palate,alveolus surgery, including respiratory depression, postoperative nausea and
vomiting, hemodynamic effects, etc.
Phase:
Phase 4
Details
Lead Sponsor:
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University