Opiate Detoxification Using the Combined Hemoperfusion-hemodialysis

• Status: Unknown status
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether combined hemoperfusion-hemodialysis treatment is an alternative drug-free, effective, and safe treatment for opiate detoxification.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: First People's Hospital of Foshan
• Treatments: Methadone

Criteria

Inclusion Criteria:

• Be fulfilled DSM-IV criteria(American Psychiatric Association) for opiate dependence.

• A history of current dependence on heroin, which was supported by laboratory results from urine drug screening, using both chromatographic and radioimmunoassay methods.

• Opioid dependent patients who inject heroin from 0.5g to 1.0g daily by veins for at least 1 year.

• Haven't received methadone treatment for at least 2 months before entry to this study.

• Be able to understand and have signed the informed consent.

Exclusion Criteria:

• Take heroin for the first time.

• Positive for HIV.

• The function of cruor or hemorrhage is badly damaged.

• The number of platelets is lower than 70×10*9.

• Co-dependent on substances other than opiates (including alcohol, benzodiazepines, cocaine, or amphetamines).

• Methadone dose requirement is over 70 mg/day as determined by the 3-day dose assessment period.

• Have serious physical illness or major psychiatric illness.

• Pregnant woman.