Overview

Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers

Status:
Completed

Trial end date:
2014-01-01

Target enrollment:

Participant gender:

Summary

A healthy volunteer study to characterise the exposure of the two study medications, following administration of OZ439 + TPGS granules with piperaquine phosphate granules (intended for children) and with piperaquine phosphate tablets (intended for adults). Ideally, to confirm the exposure demonstrated in an earlier bioavailability study.

Phase:

Phase 1

Details

Lead Sponsor:

Medicines for Malaria Venture

Collaborator:

Richmond Pharmacology Limited

Treatments:

Artefenomel
Pharmaceutical Solutions
Piperaquine