Ondansetron Versus Palonosetron Antiemetic Regimen Prior to Highly Emetogenic Chemotherapy(HEC)
Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
Palonosetron is different from ondansetron because it stays in the body longer and may
prevent nausea and vomiting for a longer period of time than ondansetron. It is standard
practice to use dexamethasone and aprepitant with either ondansetron or palonosetron to
prevent nausea and vomiting caused by highly emetogenic chemotherapy. Although these
combinations are commonly used, they have never been compared to each other. The purpose of
this study is to record the amount of nausea and vomiting, and the amount of "rescue"
medication that is used with these two different anti-emetic regimens